ESRP2 Antikörper (C-Term)

Produktnummer ABIN927996

Dieses Anti-ESRP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ESRP2 in WB. Geeignet für Human und Maus.

Kurzübersicht für ESRP2 Antikörper (C-Term) (ABIN927996)

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ESRP2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Esrp2 antibody was raised in rabbit using the C terminal of Esrp2 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Esrp2 Blocking Peptide, (ABIN5613403), is also available for use as a blocking control in assays to test for specificity of this Esrp2 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu ESRP2

Target: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Andere Bezeichnung: Esrp2

Hintergrund: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Synonyms: Polyclonal Esrp2 antibody, Anti-Esrp2 antibody, epithelial splicing regulatory protein 2 antibody, 9530027K23Rik antibody, Rbm35b antibody.